Unconjugated Mouse anti-Human ITA6 (9C5) Monoclonal Antibody [IgG1]

Výrobca: Bioss Katalógové č .: bsm-51027M Aplikácie: Imunofluorescencia, Imunohistochémia, Prietoková cytometria, Western Blot Reaktivita: Human Pôvod: Mouse Klonalita: Monoclonal Podtrieda: IgG1 Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:

CD49f; VLA-6; ITGA6B; Integrin alpha-6; CD49 antigen-like family member F; ITGA6

Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).

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