Unconjugated Rabbit anti-Dog DKK1 Polyclonal Antibody [IgG]
Výrobca: Bioss Katalógové č .: bs-2162R Aplikácie: ELISA, ELISPOT, Imunofluorescencia, Imunohistochémia Reaktivita: Dog Pôvod: Rabbit Klonalita: Polyclonal Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:SK; DKK-1; Dickkopf-related protein 1; Dickkopf-1; hDkk-1; DKK1; UNQ492/PRO18
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
100ul
415,80 EUR
s DPH