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Hana Hodoši (Hrutková)
phone+421 917 709 186 mailhodosi@ibiotech.sk Všechny kontaktyarrow

ALEXA FLUOR 750 Rabbit anti-Mouse CK12 Polyclonal Antibody, ALEXA FLUOR 750 Conjugated [IgG]

Výrobca: Bioss Katalógové č .: bs-4625R-A750 Aplikácie: Imunofluorescencia Reaktivita: Mouse Pôvod: Rabbit Klonalita: Polyclonal Konjugáty: AlexaFluor750 Laser: 750 nm (infračervený) Podtrieda: IgG Status: RUO Dodatočné informácie: Produkt na webe výrobcu Popis:

65 kDa cytokeratin; CK 12; CK 3; CK12; CK3; Cytokeratin 12; Cytokeratin 3; K12; K3; keratin 12 Meesmann corneal dystrophy; Keratin 12; Keratin 3; Keratin, type I cytoskeletal 12; K1C12_HUMAN; Keratin, type II cytoskeletal 3; KRT12; KRT3.

Cytokeratin 12 is a member of the intermediate filament family of proteins and is a heterotetramer of two type I and two type II keratins. Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12. Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Defects in KRT3 and KRT12 are a cause of Meesmann corneal dystrophy (MCD), an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Symptoms occur in adulthood and include rupture of the corneal microcysts that may lead to photophobia, contact lens intolerance and intermittent diminution of visual acuity. Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann (MCD)

100ul
519,20 EUR
s DPH
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